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Tirzepatide was removed from the shortage list in December 2024
Storage RT, stored under nitrogen Publications (22) Journal Impact Factor Most Recent Nature 2025 Jul;643(8070):192-200
Receptor activation starts
Patients should maintain adequate nutrition with focus on protein (1.01.2 g/kg daily), fibre, and nutrient-dense foods whilst avoiding severe calorie restriction without medical supervision
The main exception to this rule is the GLP-1 class (like semaglutide, tirzepatide, or retatrutide), which may be used for longer under proper supervision since the studies and pharmacology support extended duration
The injection can also help reduce muscle fatigue and support recovery by ensuring adequate nutrient availability for energy production and protein synthesis
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